:root{color:#142126;background:#f3f7f7;font-family:Inter,Microsoft YaHei,PingFang SC,Arial,sans-serif;font-synthesis:none;line-height:1.5;text-rendering:optimizeLegibility}*{box-sizing:border-box}html{scroll-behavior:smooth}body{margin:0;min-width:320px;background:linear-gradient(140deg,rgba(58,141,144,.12),transparent 36%),linear-gradient(320deg,rgba(230,120,70,.1),transparent 34%),#f3f7f7}button,input,select,textarea{font:inherit}a{color:inherit;text-decoration:none}main{width:min(1160px,calc(100% - 32px));margin:0 auto;padding:18px 0 44px}.hero{display:grid;grid-template-columns:minmax(0,1.08fr) minmax(340px,.92fr);gap:16px;align-items:stretch;min-height:250px;padding:6px 0 16px}.heroCopy,.searchPanel,.filters,.trialCard,.panel,.leadPanel{border:1px solid rgba(36,73,77,.12);box-shadow:0 18px 50px #23424614}.heroCopy{display:flex;flex-direction:column;justify-content:space-between;gap:24px;border-radius:8px;padding:clamp(24px,3vw,36px);background:linear-gradient(135deg,#126069eb,#19756fdb),linear-gradient(90deg,rgba(255,255,255,.16) 1px,transparent 1px);background-size:auto,30px 30px;color:#fff}.eyebrow{color:#e3784d;font-size:12px;font-weight:800;letter-spacing:0;margin-bottom:8px}.heroCopy .eyebrow{color:#ffd8bd;font-size:clamp(12px,1.1vw,13px);margin-bottom:0}h1,h2,h3,p{margin-top:0}h1{max-width:560px;margin-bottom:16px;font-size:clamp(36px,4.2vw,54px);line-height:1.08;letter-spacing:0}h2{margin-bottom:0;font-size:clamp(22px,2.4vw,28px);line-height:1.2;letter-spacing:0}h3{margin-bottom:8px;font-size:17px;line-height:1.3;letter-spacing:0}.heroCopy p{max-width:650px;margin-bottom:24px;color:#ffffffdb;font-size:16px;line-height:1.65}.quickLinks{display:grid;grid-template-columns:repeat(4,minmax(0,max-content));gap:8px;align-items:center}.quickLinks button,.primaryButton,.leadForm button{display:inline-flex;align-items:center;justify-content:center;min-height:42px;border:0;border-radius:6px;background:#e3784d;color:#fff;font-weight:800;font-size:15px;cursor:pointer}.quickLinks button{min-width:82px;padding:0 15px;background:#ffffff24;color:#fff;font-size:14px}.quickLinks button:hover{background:#ffffff3d}.quickLinks button.active{background:#e3784d}.pageIntro{display:flex;flex-direction:column;justify-content:center;gap:13px;border:1px solid rgba(36,73,77,.12);border-radius:8px;padding:clamp(22px,3vw,32px);background:#ffffffeb;box-shadow:0 18px 50px #23424614}.pageIntro p{color:#526a6e;margin-bottom:0;font-size:clamp(14px,1.2vw,15px);line-height:1.75}.pageIntro .eyebrow{margin-bottom:0}.pageIntro h2{font-size:clamp(24px,2.2vw,30px)}.pageIntroMeta{display:grid;gap:8px;margin-top:2px}.pageIntroMeta span{display:block;overflow:hidden;border-radius:6px;padding:9px 10px;background:#edf6f5;color:#176b65;font-size:12px;font-weight:800;text-overflow:ellipsis;white-space:nowrap}.introStats{display:grid;grid-template-columns:repeat(3,minmax(0,1fr));gap:10px;margin-top:0}.introStats span{display:grid;min-height:68px;place-items:center;border-radius:8px;background:#e6f4f2;color:#176b65;font-size:13px;font-weight:800;text-align:center}.introStats strong{display:block;font-size:24px;line-height:1}.heroStats{width:100%;grid-template-columns:repeat(3,minmax(0,1fr));gap:12px}.heroStats span{min-height:clamp(82px,7vw,96px);background:#e6f4f2f5;color:#176b65;font-size:clamp(13px,1.1vw,14px);box-shadow:inset 0 -1px #176b651f}.heroStats strong{font-size:clamp(30px,3.2vw,38px)}.searchPanel{display:grid;grid-template-columns:1fr 1fr;gap:12px;align-content:center;border-radius:8px;padding:18px;background:#ffffffeb}.searchPanel .wide,.mergedSearch .wide{grid-column:1 / -1}.mergedSearch{grid-template-columns:repeat(4,minmax(150px,1fr));align-content:start;margin-top:16px}.trialSearch{display:flex;flex-direction:column;gap:12px}.trialSearchRow{display:grid;grid-template-columns:repeat(4,minmax(0,1fr));gap:12px}label{display:grid;gap:8px;color:#486066;font-size:13px;font-weight:800}select,input,textarea{width:100%;min-height:42px;border:1px solid #c9d8d9;border-radius:6px;padding:0 12px;background:#fff;color:#142126;outline:none}select:focus,input:focus,textarea:focus{border-color:#19756f;box-shadow:0 0 0 3px #19756f24}.workspace,.pageShell{display:grid;grid-template-columns:260px minmax(0,1fr);gap:16px;align-items:start;margin-top:16px}.pageShell.single{grid-template-columns:1fr}.filters,.panel{border-radius:8px;background:#ffffffe0}.filters{position:sticky;top:16px;display:grid;gap:12px;padding:16px}.filters h2{font-size:18px}.results{min-width:0}.sectionHeader{display:flex;align-items:end;justify-content:space-between;gap:16px;margin-bottom:14px}.sectionHeader span{color:#60777b;font-size:13px;font-weight:700}.trialList{display:grid;gap:12px}.trialCard{border-radius:8px;padding:18px;background:#fff}.cardTop{display:flex;align-items:center;justify-content:space-between;gap:12px;margin-bottom:12px}.cardTopLeft{display:flex;align-items:center;flex-wrap:wrap;gap:10px;min-width:0}.score,.status,.trialIdBadge,.pill{display:inline-flex;align-items:center;min-height:28px;border-radius:999px;padding:0 10px;font-size:13px;font-weight:900}.score{background:#e6f4f2;color:#176b65}.trialIdBadge{border:1px solid #d4e4e3;background:#f7fbfa;color:#4b6468;max-width:220px;overflow:hidden;text-overflow:ellipsis;white-space:nowrap}.status{background:#eef1f1;color:#526a6e}.status.open,.pill{background:#fff1e9;color:#bd5531}.trialCard p,.panel p,.leadPanel p{color:#526a6e;font-size:15px;line-height:1.65}.metaGrid{display:grid;grid-template-columns:repeat(2,minmax(0,1fr));gap:8px;margin:12px 0}.metaGrid span{min-height:32px;border-radius:6px;padding:7px 9px;background:#f4f8f8;color:#354b50;font-size:12px;font-weight:700}.metaGrid.compact{grid-template-columns:1fr}.tagRow{display:flex;flex-wrap:wrap;gap:8px;margin-bottom:16px}.tagRow span{border:1px solid #d8e4e5;border-radius:999px;padding:4px 9px;color:#526a6e;font-size:12px;font-weight:800}.primaryButton{width:fit-content;padding:0 16px}.secondaryButton{display:inline-flex;align-items:center;justify-content:center;min-height:42px;border:1px solid #c9d8d9;border-radius:6px;padding:0 14px;background:#fff;color:#176b65;font-weight:900;cursor:pointer}.primaryButton:hover,.quickLinks button.active,.quickLinks button:hover{background:#ef7a4c}.secondaryButton:hover{border-color:#19756f;background:#e6f4f2}.secondaryButton.active{border-color:#19756f;background:#19756f;color:#fff}.formHint{margin:8px 0 0;font-size:12px;color:#6b7e80;line-height:1.5}.cardActions{display:flex;flex-wrap:wrap;gap:10px}.detailActions{display:flex;flex-wrap:wrap;gap:10px;justify-content:flex-end}.detailPanel{margin-top:0;border:1px solid rgba(36,73,77,.12);border-radius:8px;padding:20px;background:#173f43;color:#fff;box-shadow:0 18px 50px #23424614}.detailPanel p,.detailPanel .sectionHeader span{color:#ffffffc7}.detailPanel .secondaryButton{border-color:#ffffff4d;background:#ffffff1a;color:#fff}.detailPanel .secondaryButton:hover{background:#ffffff2e}.detailPanel .metaGrid span{background:#ffffff1a;color:#fff}.detailGrid{display:grid;grid-template-columns:repeat(2,minmax(0,1fr));gap:12px}.detailBlock{border-radius:8px;padding:14px;background:#ffffff1a}.detailBlock h3{color:#fff}.detailBlock .tagRow{margin-bottom:0}.detailBlock .tagRow span{background:#ffffff1f;color:#fff}.panel{padding:20px}.hospitalList{display:grid;gap:10px}.hospitalItem{display:grid;grid-template-columns:minmax(0,1fr) auto;gap:16px;align-items:center;border-bottom:1px solid #e3ebeb;padding:0 0 12px}.hospitalItem:last-child{border-bottom:0;padding-bottom:0}.hospitalItem h3{margin-bottom:4px}.hospitalItem p{margin-bottom:0;font-size:13px}.visitButton{display:inline-flex;align-items:center;justify-content:center;min-width:82px;min-height:38px;border-radius:6px;background:#e3784d;color:#fff;font-weight:900}.visitButton.muted{background:#eef1f1;color:#60777b}.drugDirectory{display:grid;grid-template-columns:repeat(3,minmax(0,1fr));gap:12px;margin-bottom:0}.drugDirectoryCard{border:1px solid #d7e5e5;border-radius:8px;padding:14px;background:#f8fbfb}.drugDirectoryCard h3{margin-top:10px;font-size:17px}.leadPanel{display:grid;grid-template-columns:.8fr 1.2fr;gap:24px;align-items:start;margin-top:16px;border-radius:8px;padding:22px;background:#173f43;color:#fff}.leadPanel p{color:#ffffffc7}.leadForm{display:grid;grid-template-columns:1fr 1fr;gap:12px}.leadForm label{color:#ffffffe0}.leadForm .wide,.leadForm button,.formMessage{grid-column:1 / -1}textarea{min-height:86px;padding-top:10px;resize:vertical}.leadForm button{min-height:46px}.formMessage{margin:0;border-radius:6px;padding:10px 12px;font-weight:800}.formMessage.error{background:#c4422e2e;color:#ffd5cf}.formMessage.success{background:#44a88233;color:#d7fff1}.adminPanel{display:grid;gap:18px}.adminGrid{display:grid;grid-template-columns:repeat(3,minmax(0,1fr));gap:12px}.adminCard{border-radius:8px;padding:16px;background:#e6f4f2;color:#176b65}.adminCard span{font-size:13px;font-weight:900}.adminCard strong{display:block;margin:8px 0;font-size:32px;line-height:1}.adminCard p{margin:0;color:#486066;font-size:13px}.adminWorkArea{display:grid;grid-template-columns:.9fr 1.1fr;gap:14px}.adminForm{display:grid;gap:12px;border:1px solid #d7e5e5;border-radius:8px;padding:16px;background:#f8fbfb}.adminForm h3{margin-bottom:0}.adminForm .primaryButton,.adminForm .secondaryButton{width:fit-content}.adminStatusBox{display:grid;gap:8px}.adminStatusBox span,.releaseFlow span{border-radius:6px;padding:9px 10px;background:#fff;color:#354b50;font-size:13px;font-weight:800}.releaseFlow{display:grid;gap:12px;border-radius:8px;padding:16px;background:#173f43;color:#fff}.releaseFlow h3{margin-bottom:0;color:#fff}.releaseFlow div{display:grid;grid-template-columns:repeat(5,minmax(0,1fr));gap:10px}.adminColumns{display:grid;grid-template-columns:repeat(4,minmax(0,1fr));gap:16px;align-items:start}.adminColumn{display:grid;gap:14px;border-radius:12px;padding:16px;border:1px solid rgba(36,73,77,.12);background:#fff;box-shadow:0 10px 34px #2342460f}.adminColumnTrials{border-top:4px solid #2a9d8f;background:linear-gradient(180deg,#f4fbfa,#fff 120px)}.adminColumnHospitals{border-top:4px solid #4a90e2;background:linear-gradient(180deg,#f4f9ff,#fff 120px)}.adminColumnDrugs{border-top:4px solid #e3784d;background:linear-gradient(180deg,#fff7f4,#fff 120px)}.adminColumnLeads{border-top:4px solid #9b59b6;background:linear-gradient(180deg,#f9f4fb,#fff 120px)}.adminColumnHeader{display:flex;justify-content:space-between;align-items:flex-start}.adminColumnHeader .eyebrow{margin-bottom:4px}.adminColumnHeader h3{margin:0;font-size:18px;color:#142126}.adminColumnHeader strong{font-size:28px;line-height:1;color:#142126}.adminColumnDesc{margin:-8px 0 0;color:#5a6e72;font-size:13px;line-height:1.5}.adminColumnSection{display:grid;gap:10px;border-radius:10px;padding:14px;background:#ffffffb8;border:1px solid rgba(36,73,77,.08)}.adminColumnSection h4{margin:0;font-size:14px;color:#142126;font-weight:800}.adminColumnSection p{margin:0;font-size:12px;color:#5a6e72}.adminColumnToolbar{display:flex;gap:8px}.adminFilterInput{flex:1;min-width:0;height:38px;padding:0 12px;border:1px solid rgba(36,73,77,.18);border-radius:6px;font-size:13px;outline:none;transition:border-color .15s}.adminFilterInput:focus{border-color:#196f6f}.adminColumnToolbar .primaryButton{min-height:38px;padding:0 14px;font-size:13px}.adminList{max-height:280px;overflow-y:auto;border:1px solid rgba(36,73,77,.1);border-radius:8px;background:#fff}.adminListItem{display:flex;justify-content:space-between;align-items:flex-start;gap:8px;padding:10px 12px;border-bottom:1px solid rgba(36,73,77,.08)}.adminListItem:last-child{border-bottom:0}.adminListItemBody{flex:1;min-width:0}.adminListItemBody strong{display:inline-block;margin-right:8px;font-size:12px;font-family:monospace;color:#142126}.adminListItemBody span{font-size:11px;color:#6f8589}.adminListItemBody>div{margin-top:4px;font-size:12px;overflow:hidden;text-overflow:ellipsis;white-space:nowrap;color:#142126}.adminListItemActions{display:flex;gap:6px;flex-shrink:0}.adminListItemActions .secondaryButton{min-height:28px;padding:0 10px;font-size:12px}.adminListItemActions .secondaryButton.danger{color:#e74c3c}.adminEmpty{margin:0;padding:14px;text-align:center;font-size:12px;color:#8a9b9e}.adminStatusBox.compact{gap:6px}.adminStatusBox.compact span{padding:6px 8px;font-size:11px}.sourceList{display:grid;gap:8px;max-height:150px;overflow-y:auto}.sourceItem{display:flex;align-items:flex-start;justify-content:space-between;gap:8px;border:1px solid rgba(36,73,77,.1);border-radius:8px;padding:8px;background:#fff}.sourceItem div{min-width:0}.sourceItem strong{display:block;color:#142126;font-size:12px}.sourceItem span{display:block;overflow:hidden;color:#6f8589;font-size:11px;text-overflow:ellipsis;white-space:nowrap}.sourceForm{display:grid;grid-template-columns:minmax(0,.85fr) minmax(0,1.15fr);gap:8px}.sourceForm .secondaryButton{grid-column:1 / -1;min-height:34px}.sourceForm input{min-height:36px;padding:0 10px;font-size:12px}.iconTextButton{flex:0 0 auto;min-height:28px;border:1px solid rgba(231,76,60,.25);border-radius:6px;padding:0 9px;background:#fff;color:#e74c3c;font-size:12px;font-weight:800;cursor:pointer}.formError{color:#e74c3c!important;font-weight:800}.adminFileActions{display:flex;gap:8px}.fileButton{position:relative;overflow:hidden;cursor:pointer}.fileButton input{position:absolute;inset:0;opacity:0;cursor:pointer}.adminModeSelect{display:grid;gap:6px;font-size:12px;color:#5a6e72}.adminModeSelect select{height:34px;padding:0 10px;border:1px solid rgba(36,73,77,.18);border-radius:6px;background:#fff;font-size:13px}.adminGlobalActions{display:grid;grid-template-columns:repeat(2,minmax(0,1fr));gap:14px}@media(max-width:900px){main{width:min(100% - 20px,720px);padding-top:12px}.hero,.workspace,.pageShell,.leadPanel{grid-template-columns:1fr}.hero{min-height:auto;gap:12px}.heroCopy{gap:18px}.quickLinks{grid-template-columns:repeat(4,minmax(0,1fr))}.quickLinks button{min-width:0;padding:0 10px}.filters{position:static;grid-template-columns:1fr 1fr}.filters h2{grid-column:1 / -1}.mergedSearch,.trialSearchRow,.detailGrid,.drugDirectory,.adminGrid,.adminWorkArea,.adminColumns,.adminGlobalActions,.releaseFlow div{grid-template-columns:1fr 1fr}}@media(min-width:901px)and (max-width:1120px){h1{font-size:46px}.drugDirectory{grid-template-columns:repeat(2,minmax(0,1fr))}}@media(max-width:560px){main{width:min(100% - 14px,480px);padding-top:8px}h1{font-size:34px}.heroCopy,.searchPanel,.trialCard,.panel,.leadPanel{padding:16px}.heroCopy{gap:16px}.heroCopy .eyebrow{font-size:12px}.heroStats{grid-template-columns:repeat(3,minmax(0,1fr));gap:8px}.heroStats span{min-height:72px;padding:8px 4px;font-size:12px}.heroStats strong{font-size:26px}.quickLinks{grid-template-columns:repeat(2,minmax(0,1fr))}.quickLinks button{min-height:38px;font-size:13px}.pageIntro{padding:16px;gap:10px}.pageIntro h2{font-size:22px}.pageIntro p{font-size:14px;line-height:1.65}.pageIntroMeta span{white-space:normal;line-height:1.45}.searchPanel,.filters,.metaGrid,.introStats,.mergedSearch,.trialSearchRow,.detailGrid,.leadForm,.drugDirectory,.adminGrid,.adminWorkArea,.adminColumns,.adminGlobalActions,.releaseFlow div{grid-template-columns:1fr}.heroStats{grid-template-columns:repeat(3,minmax(0,1fr))}.adminColumnToolbar{flex-wrap:wrap}.adminColumnToolbar .primaryButton{width:auto}.adminFileActions{flex-wrap:wrap}.sectionHeader,.hospitalItem{align-items:start;grid-template-columns:1fr}.sectionHeader{display:grid}.primaryButton,.cardActions,.secondaryButton{width:100%}}.adminEntry{position:fixed;right:16px;bottom:16px;z-index:50;padding:7px 16px;border:1px solid rgba(36,73,77,.18);border-radius:20px;background:#ffffffb8;color:#24494d73;font-size:12px;font-weight:600;cursor:pointer;-webkit-backdrop-filter:blur(8px);backdrop-filter:blur(8px);transition:color .2s,border-color .2s,background .2s}.adminEntry:hover{color:#24494de0;border-color:#24494d61;background:#ffffffeb}.adminLoginOverlay{position:fixed;inset:0;z-index:100;display:flex;align-items:center;justify-content:center;background:#12282b7a;-webkit-backdrop-filter:blur(4px);backdrop-filter:blur(4px)}.adminLoginModal{width:min(360px,90vw);padding:30px 26px 24px;border-radius:12px;background:#fff;box-shadow:0 26px 76px #12282b4d;animation:adminModalIn .2s ease-out}@keyframes adminModalIn{0%{opacity:0;transform:translateY(12px) scale(.97)}to{opacity:1;transform:translateY(0) scale(1)}}.adminLoginModal h3{margin:6px 0 16px;font-size:18px;color:#142126}.adminLoginModal input{width:100%;height:44px;padding:0 14px;border:1px solid rgba(36,73,77,.22);border-radius:6px;font-size:15px;outline:none;transition:border-color .15s}.adminLoginModal input:focus{border-color:#196f6f}.adminLoginError{display:block;margin-top:8px;color:#d94545;font-size:13px;font-weight:600}.adminLoginActions{display:flex;gap:10px;margin-top:20px}.adminLoginActions button{flex:1}.trialFormModal{background:#f3f7f7;border-radius:12px;padding:24px;max-width:720px;width:95%;max-height:90vh;overflow-y:auto;margin:20px auto;box-shadow:0 20px 60px #0003}.trialFormModal h3{margin:4px 0 0;font-size:20px;color:#142126}.trialFormModal label{display:flex;flex-direction:column;gap:4px;font-size:13px;font-weight:600;color:#4a5558}.trialFormModal label span{font-weight:400}.trialFormModal input,.trialFormModal select,.trialFormModal textarea{padding:8px 10px;border:1px solid #cbd5d6;border-radius:6px;font-size:13px;font-family:inherit;background:#fff;color:#142126}.trialFormModal input:focus,.trialFormModal select:focus,.trialFormModal textarea:focus{outline:none;border-color:#196f6f;box-shadow:0 0 0 2px #196f6f26}.trialFormModal textarea{resize:vertical;min-height:52px}.trialManageList{margin-top:8px;background:#fff;border:1px solid #cbd5d6;border-radius:8px;overflow:hidden}.trialManageList>div:last-child{border-bottom:none}.trialManageList>div:hover{background:#f0f5f5}.tagPresetGrid{display:flex;flex-direction:column;gap:6px}.tagPresetGroup{display:flex;align-items:flex-start;gap:8px}.tagPresetLabel{min-width:80px;font-size:12px;font-weight:600;color:var(--text-secondary);padding-top:4px;text-align:right}.tagPresetChips{display:flex;flex-wrap:wrap;gap:4px;flex:1}.tagChip{display:inline-flex;align-items:center;padding:2px 10px;border-radius:12px;font-size:11px;line-height:1.6;cursor:pointer;border:1.5px solid var(--border);background:var(--bg-page);color:var(--text-secondary);transition:all .15s;white-space:nowrap}.tagChip:hover{border-color:var(--primary);color:var(--primary)}.tagChipActive{background:#007a801f;border-color:var(--primary);color:var(--primary);font-weight:600}.trialTags{display:flex;flex-wrap:wrap;gap:3px;margin-top:4px}.trialTagBadge{display:inline-block;padding:1px 8px;border-radius:10px;font-size:10px;background:#007a8014;color:var(--primary);border:1px solid rgba(0,122,128,.2);white-space:nowrap}.adminTrialTags{display:flex;flex-wrap:wrap;gap:3px;margin-top:2px}